Secondary antiphospholipid syndrome at a young male

Antiphospholipid syndrome (APS) is an autoimmune disease characterized by recurring venous and/or arterial thrombosis and the presence of circulating antiphospholipid antibodies. APS occurs as a primary condition or secondary to other disorders, mainly systemic lupus erythematosus (SLE). The diagnosis made on basis suggestive clinical findings one more following antibodies (LAC, aCL antibody aβ2GPI present two occasions, at least 12 weeks part). A clinically significant aPL profile has been detected in approximately 30 % patients with SLE. Case presentation: We are presenting rare case 23 years old male complaints dyspnea, retrosternal discomfort, fatigue, general weakness, joint pain over period 3 months. patient reported single syncopal episode, months prior admission his first manifestation. He was diagnosed Thrombocytopenia 2007 Systemic Lupus Erythematosus (SLE) 2020. During hospitalization, experienced recurrent headaches, dizziness episodes elevated blood pressure (170/100 mmHg), well. Moreover, laboratory imaging examinations showed bilateral pulmonary thromboembolism positive Anticardiolipin antibodies, ANA, SSA & SSB. Conclusion: Given lack typical early stages disease, establishing can be challenging. Although most common thrombocytophilias, unfortunately, it remains underdiagnosed. Clinicians should investigate for may influence course disease.